Friday, December 31, 1999

Schizophrenia: Two Models Of Schizophrenia

Yale Study Reconciles Two Models Of Schizophrenia: "Yale School of Medicine researchers published a report this month in the Archives of General Psychiatry that highlights the interplay of two brain signaling systems, glutamate and dopamine, in psychosis and cognitive function.

"This study lends support to the hypothesis that drugs that facilitate the function of particular dopamine receptors might play a role in treating cognitive impairments associated with schizophrenia," Krystal said.

Co-authors include Edward Perry Jr., M.D., Ralitza Gueorguieva, Aysenil Belger, Steven Madonick, M.D., Anissa Abi-Dargham, M.D., Thomas Cooper, Lisa MacDougall, Walid Abi-Saab, M.D., and Cyril D'Souza, M.D.

Archives of General Psychiatry 62: 985-995 (September 2005)
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