Schizophrenia: Morphological brain changes associated with Schneider's first-rank symptoms in schizophrenia: a MRI study.

Entrez PubMed: "Schneider's first-rank symptoms involve an alienated feature of the sense of one's own mental or physical activity. To clarify the brain morphological basis for the production of these symptoms, volumes of the frontal and medial temporal regions and their clinical correlates were examined in patients with schizophrenia. . . Patients had significantly decreased volumes in the cingulate gray matter and the amygdala compared to controls. In the patient group, Schneiderian symptom severity showed significant inverse correlations with volumes of the right posterior cingulate gray matter and of the left anterior parahippocampal gyrus. Schneiderian symptoms may be associated with morphological abnormalities in the limbic-paralimbic regions such as the cingulate gyrus and parahippocampal gyrus, which possibly serve the self-monitoring function and the coherent storage and reactivation of information.
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Morphological brain changes associated with Schneider's first-rank symptoms in schizophrenia: a MRI study.
Suzuki M, Zhou SY, Hagino H, Niu L, Takahashi T, Kawasaki Y, Matsui M, Seto H, Ono T, Kurachi M.
Psychol Med. 2005 Apr;35(4):549-60.