Imaging: Emotion: The neural bases of amusement and sadness: a comparison of block contrast and subject-specific emotion intensity regression approach

Entrez PubMed: "For sad films, both block contrast and subject-specific regression approaches resulted in activations in medial prefrontal cortex, inferior frontal gyrus, superior temporal gyrus, precuneus, lingual gyrus, amygdala, and thalamus. For amusing films, the subject-specific regression analysis demonstrated significant activations not detected by the block contrast in medial, inferior frontal gyrus, dorsolateral prefrontal cortex, posterior cingulate, temporal lobes, hippocampus, thalamus, and caudate. These results suggest a relationship between emotion-specific temporal dynamics and the sensitivity of different data analytic methods for identifying emotion-related neural responses. These findings shed light on the neural bases of amusement and sadness, and highlight the value of using emotional film stimuli and subject-specific continuous emotion ratings to characterize the dynamic, time-varying components of emotional responses."

The neural bases of amusement and sadness: a comparison of block contrast and subject-specific emotion intensity regression approaches.
Goldin PR, Hutcherson CA, Ochsner KN, Glover GH, Gabrieli JD, Gross JJ.
Neuroimage. 2005 Aug 1;27(1):26-36.