Monday, January 01, 1990

Depression: CBT: Modulation of cortical-limbic pathways in major depression: treatment-specific effects of cognitive behavior therapy.

Entrez PubMed: "Functional imaging studies of major depressive disorder demonstrate response-specific regional changes following various modes of antidepressant treatment. . . Like other antidepressant treatments, CBT (cognitive behaviour therapy) seems to affect clinical recovery by modulating the functioning of specific sites in limbic and cortical regions. Unique directional changes in frontal cortex, cingulate, and hippocampus with CBT relative to paroxetine may reflect modality-specific effects with implications for understanding mechanisms underlying different treatment strategies."

Modulation of cortical-limbic pathways in major depression: treatment-specific effects of cognitive behavior therapy.
Goldapple K, Segal Z, Garson C, Lau M, Bieling P, Kennedy S, Mayberg H.
Arch Gen Psychiatry. 2004 Jan;61(1):34-41.
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